Search Results - chemistry and biochemistry

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Spindle Assembly Checkpoint Inhibition for Treatment of p53 Deficient Cancers
Reference #: 01405 The University of South Carolina is offering licensing opportunities for Re-sensitizing p53-null Stem Cells with Spindle Assembly Checkpoint Inhibition Background: TP53 is one of the most well-studied tumor suppressor genes and is known to be pivotal in response to DNA damage for cell cycle arrest, deterioration with age, or cell...
Published: 10/24/2019   |   Inventor(s): Phillip Buckhaults, Carolyn Banister, Changlong Liu
Keywords(s):  
Category(s): Chemistry and Biochemistry
The Preparation of Dual-Targeted Nano-Cocktail and its Application in Cancer Therapy
Reference #: 01404 The University of South Carolina is offering licensing opportunities for Preparation of Dual-Targeted Nano-Cocktail and its Application in Cancer Therapy Background: Due to the heterogeneous nature of tumors and the limitation of anticancer drugs, a mono-compound treatment usually can only kill a fraction of cancer cells while...
Published: 10/24/2019   |   Inventor(s): Peisheng Xu, Binglin Sui
Keywords(s):  
Category(s): Chemistry and Biochemistry
Inhibitors of Glucose Kinases: Update 2-27-2019
Reference #: 01401 The University of South Carolina is offering licensing opportunities for Monosaccharide Amine and 3-Nitro-2-Phenyl-2H-Chromene Based Inhibitors of Glucose Kinases Background: When a kissing bug bites a human, they can be infected with a Kinetoplastid parasite such as Trypanosoma cruzi (T. cruzi). A need exists for new drugs that...
Published: 10/24/2019   |   Inventor(s): Edward D'antonio
Keywords(s):  
Category(s): Chemistry and Biochemistry, Biomedical and Life Sciences
Dot Blot Box for Detection of Blotted Protein
Reference #: 01271 The University of South Carolina is offering licensing opportunities for Dot Blot Box for Detection of Blotted Protein Background: The cause of Alzheimer’s disease is believed to lie within the aggregation and subsequent accumulation of the amyloid-b (Ab) protein. Observation of amyloid-b aggregation requires readings or...
Published: 10/23/2019   |   Inventor(s): Melissa Moss, Lauren Wolf
Keywords(s):  
Category(s): Biomedical and Life Sciences, Chemistry and Biochemistry
Gas Separation Membranes From Polymer-Grafted Nanoparticles
Reference #: 01418 The University of South Carolina is offering licensing opportunities for Gas Separation Membranes from Polymer-grafted Nanoparticles Background: Polymeric membranes are critical to many sustainability applications that separate gas mixtures based on size differences. Polymer blends using polymer grafted nanoparticles with small...
Published: 7/12/2019   |   Inventor(s): Brian Benicewicz (USC), Yucheng Huang, Connor Bilchak, Sanat Kumar
Keywords(s):  
Category(s): Chemistry and Biochemistry
Fabrication of Suramin-loaded Nanoparticle and its Application
Reference #: 01386The University of South Carolina is offering licensing opportunities for the fabrication of suramin loaded nanoparticle and its application.Background:Most anti-cancer drugs damage normal cells as they kill cancer cells, causing patients to suffer from side effects like heart tissue and kidney damage. It has been shown that suramin...
Published: 3/15/2019   |   Inventor(s): Peisheng Xu
Keywords(s):  
Category(s): Chemistry and Biochemistry
Apparatus for Detection of Molecule-Nanoparticle Interactions
Reference #: 01344The University of South Carolina is offering licensing opportunities for an Apparatus for Detection of Molecule-Nanoparticle InteractionsBackground:Nanoparticles have widespread applications, from sensing to drug delivery, where much behavior is determined by the nature of the surface and the resulting intermolecular interactions with...
Published: 2/27/2019   |   Inventor(s): Morgan Stefik, Zachary Marsh
Keywords(s):  
Category(s): Chemistry and Biochemistry
Pharmabiotic Approaches to Treat Phenylalanine Hydroxylase Deficiency
Reference #: 01317The University of South Carolina is offering licensing opportunities for Pharmabiotic Approaches to Treat Phenylalanine Hydroxylase DeficiencyBackground:Approximately 1 in 15,000 persons in the US have phenylalanine hydroxylase deficiency. It is stated in the American College of Medical Genetics clinical practice guidelines for the...
Published: 1/10/2019   |   Inventor(s): Michael Wyatt, Chloe LeBegue, Jacob Massey
Keywords(s):  
Category(s): Chemistry and Biochemistry, Health Sciences, Biomedical and Life Sciences
New Polar Oxysufide for Nonlinear Optical Applications
Reference #: 01327The University of South Carolina is offering licensing opportunities for New Polar Oxysufide for Nonlinear Optical ApplicationsBackground:Non-linear optical materials are commonly used for frequency doubling diode-pumped solid state lasers such as Nd:YAG or other Nd-doped lasers, and are also used as optical parametric oscillator for...
Published: 9/7/2018   |   Inventor(s): Hans-Conrad Zur Loye, Yoshihiro Tsujimoto He
Keywords(s):  
Category(s): Chemistry and Biochemistry
Macrocyclic Dimerization Inhibitors of Raf Kinases
Reference #: 01338The University of South Carolina is offering licensing opportunities for Macrocyclic Dimerization Inhibitors of Raf Kinases.Background:Despite the clinical success of B-Raf inhibitors like vemurafenib in treating metastatic melanoma, resistance has emerged through “paradoxical MEK/ERK signaling” where rather than blocking...
Published: 9/7/2018   |   Inventor(s): Campbell Mcinnes
Keywords(s):  
Category(s): Chemistry and Biochemistry, Biomedical and Life Sciences
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