Latest technologies from University of South Carolina the first to know about the latest inventions and technologies available from University of South Carolinaen-USMon, 10 Dec 2018 17:52:52 GMTThu, 01 Nov 2018 11:55:56 GMT 2018, University of South CarolinaCulture Medium for Human Skin Explants Enabling Molecular Studies, 01 Nov 2018 11:55:56 GMTtechnology@sc.edu Vapor Quantification Methodology During Drying of Spent Nuclear Fuel, 01 Nov 2018 09:39:15 GMTtechnology@sc.edu Estimation of the Mechanical Properties of the Heart, 12 Oct 2018 10:16:41 GMTtechnology@sc.edu and Automated Video/Structural Health Monitoring System, 12 Oct 2018 09:16:34 GMTtechnology@sc.edu Polar Oxysufide for Nonlinear Optical Applications, 07 Sep 2018 11:37:06 GMTtechnology@sc.edu Dimerization Inhibitors of Raf Kinases, 07 Sep 2018 10:32:44 GMTtechnology@sc.edu Decomposition Catalyst, 24 Aug 2018 12:40:46 GMTtechnology@sc.edu Cells Biomarkers for the Identification of Viable Embryos, 10 Aug 2018 11:05:50 GMTtechnology@sc.edu Decellularized Tissue as Microcarrier for Cell Culture and Expansion, 09 Aug 2018 09:27:36 GMTtechnology@sc.edu Fiber Optic Temperature Field Measurement During Thermoplastic Composite Welding, 01 Aug 2018 12:13:33 GMTtechnology@sc.edu Synthesis Inhibitors for Depression Treatment, 01 Aug 2018 09:23:07 GMTtechnology@sc.edu Imaging for Quantification of Complex Discontinuity in Plate-like Structures, 22 Jun 2018 09:32:25 GMTtechnology@sc.edu Generation of Lighting Phosphors based on stable Oxyflouride Host Lattice, 07 Jun 2018 10:57:46 GMTtechnology@sc.edu Scintillating Materials, 05 Jun 2018 09:52:28 GMTtechnology@sc.edu White Light Phosphors, 05 Jun 2018 09:32:52 GMTtechnology@sc.edu Sterilization of Tissue Engineering Scaffolds with Compressed Carbon Dioxide #: 00774The University of South Carolina is offering licensing opportunities for this technologyInvention Description:A process for sterilizing tissue engineering materials by using compressed carbon dioxide into which selected additives have been incorporated. This method is effective for sterilizing complex structures, without causing adverse effects to the structure of the material.Potential Applications:This invention is extremely useful for sterilizing tissue engineering materials, including but not limited to synthetic polymers and natural polymers, without causing degradation ...Mon, 04 Jun 2018 08:05:12 GMTtechnology@sc.edu and Characterization of TP53-null MCF7 Breast Cancer Cells, 18 May 2018 10:17:49 GMTtechnology@sc.edu Global-Local (AGL) Prediction of Guided Wave Scattering from Discontinuities, 18 May 2018 06:31:21 GMTtechnology@sc.edu 3D-Vision System for Rail Neutral Temperature Measurements, 02 May 2018 13:21:39 GMTtechnology@sc.edu Field Effect Transistors for Detection of Potassium Ions, 06 Apr 2018 11:27:51 GMTtechnology@sc.edu as a Diagnostic and Therapeutic Target for Breast Cancer, 06 Apr 2018 11:03:21 GMTtechnology@sc.edu FBMC Wireless Communication System, 04 Apr 2018 10:58:39 GMTtechnology@sc.edu Inhibition of the Polo-Like Kinase 1 PBD for Cancer Therapy, 30 Mar 2018 09:53:11 GMTtechnology@sc.edu Membrane Coated Nanoparticle for Brain Targeted Drug Delivery, 30 Mar 2018 09:01:24 GMTtechnology@sc.edu Marker for FQAD, Drug Toxicity, and Vaccine Toxicity, 26 Mar 2018 12:47:45 GMTtechnology@sc.edu Active Decomposition Catalyst for Low Carbon Hydrocarbon Production from Sulfur Containing Fuel Reference #: 00916 The University of South Carolina is offering licensing opportunities for this technology. Potential Applications: The basic application of the disclosed catalytic materials is targeted towards enabling portable fuel cells running on non-desulfurised jet fuel, in particular strategic military fuel (JP-8). Advantages and Benefits: Useful for the conversion of sulphur containing, high-C hydrocarbon fuel The conversion efficiency can be up to 23%, calculated on a mass basis. However it is envisioned that higher conversion efficiencies may be realized through optimizat...Fri, 02 Mar 2018 10:38:44 GMTtechnology@sc.edu using Multivariate Optical Computing, 01 Mar 2018 11:17:32 GMTtechnology@sc.edu Doped III-nitride High Electron Mobility Transistor, 16 Feb 2018 13:27:12 GMTtechnology@sc.edu and Methods for Liquid Fuel Desulfurization, 16 Feb 2018 12:03:50 GMTtechnology@sc.edu of Growing High Quality, Thick SiC Epitaxial Films at High Growth Rates in a Hotwall CVD Reactor, 16 Feb 2018 10:13:06 GMTtechnology@sc.edu Acousto-Ultrasonic Piezoelectric-Fiber Bragg Grating (P-FBG) Sensor, 16 Feb 2018 09:48:39 GMTtechnology@sc.edu and Compositions for Inactivating Allergens and Allergen-Producing Organisms #: 00690The University of South Carolina is offering licensing opportunities for this technologyPotential Applications:This technology has the potential to be used on a full-scale industrial level for purposes such as home carpet cleaning.Advantages and Benefits:With the combination of killing and removing dust mites and dust mite feces, indoor allergen levels will be significantly lowered compared to the usual deep vacuum cleaning method. More powerful, but still non-toxic, alternative to traditionally ineffective vacuuming Leaves no soluble solvent residuals Invention Description:A...Fri, 02 Feb 2018 09:05:58 GMTtechnology@sc.edu of Bacterial Endotoxins #: 00803Background:Bacterial endotoxins are residues from gram negative bacteria that can cause serious health problems if introduced into the blood stream. Therefore, bacterial endotoxins are a serious concern for companies in the reusable medical device field. Invention Description:The invention consists of a cleaning method for the complete removal of endotoxins from biomaterials and metallic substrates.Potential Applications:Hospitals, Clinics, Out-patient surgery centers, and Any company that requires endotoxin removal from reusable medical devices Small clinical settings wi...Fri, 02 Feb 2018 09:02:39 GMTtechnology@sc.edu Electrically Tunable 3-D Compact RF Phase Shifter, 25 Jan 2018 06:47:28 GMTtechnology@sc.edu Learning to Identify Locations of Brain Injury, 19 Jan 2018 12:30:08 GMTtechnology@sc.edu Tunable Highly Active Metal Oxides for Tri-Reforming of Methane, 19 Jan 2018 10:47:46 GMTtechnology@sc.edu Nickle-Graphene Interface for Highly Efficient and Durable Condensers, 12 Jan 2018 12:25:11 GMTtechnology@sc.edu in Therapy/Prevention of Inflammation, Obesity, and Metabolic Syndrome, 27 Oct 2017 12:22:02 GMTtechnology@sc.edu Composite for Hydrogen Separation Membranes, 27 Oct 2017 12:13:28 GMTtechnology@sc.edu Substrate Supported Microtubular Solid Oxide Cells, 27 Oct 2017 11:41:29 GMTtechnology@sc.edu Matrix for Enriching Malignant Cancer Stem Cells #: 01067 The University of South Carolina is offering licensing opportunities for a novel system for testing cancer drugs. Invention Description: Cancer recurrence or relapse is related to a very small population of highly-malignant and metastasizing cancer stem cells that have the ability initiate, propagate, and maintain the cancer tissue. This invention is a material composition that allows the growth and survival of cancer initiating/stem cells, or those cancer cells that are resistant to therapy. When any cancer cell line is embedded in the material composition of this invention...Fri, 06 Oct 2017 12:42:05 GMTtechnology@sc.edu Fuel Converter: Transportation Fuels to LPG, 06 Oct 2017 07:59:36 GMTtechnology@sc.edu of Thermoplastic Composites Using Vacuum-Bagging, Air-Cooling, and Induction, 29 Sep 2017 09:34:30 GMTtechnology@sc.edu - A Method to Manipulate Gene Silencing in Plants, 29 Sep 2017 07:24:57 GMTtechnology@sc.edu Control Algorithm for Power Hardware in the Loop Systems, 15 Sep 2017 12:40:09 GMTtechnology@sc.edu Wound Healing Composition of Myricetin-3-O-rhamnoside and Chlorogenic Acid, 15 Sep 2017 11:53:47 GMTtechnology@sc.edu Ink Based Single-Swipe Detection of Treated Lumber, 08 Sep 2017 08:49:31 GMTtechnology@sc.edu of Succination as a Measure of Fumarate Ester Efficacy, 25 Aug 2017 06:55:26 GMTtechnology@sc.edu Enabled 3D Enrichment of Cancer Stem Cells, 15 Aug 2017 10:13:44 GMTtechnology@sc.edu Uptake by Cancer Stem Cells via Conjugation Silica Nanoparticles, 15 Aug 2017 10:07:08 GMTtechnology@sc.edu Reduced-Elastic Modulus Concrete for Railroad Tie Applications, 11 Aug 2017 11:30:48 GMTtechnology@sc.edu Sulfide (H2S) Releasing Donor Compound for Dermal Wound Regeneration, 04 Aug 2017 10:21:26 GMTtechnology@sc.edu as a New Biomarker in Breast Cancer, 04 Aug 2017 09:58:54 GMTtechnology@sc.edu Markers and Uses for CDK7 Inhibitors, 28 Jul 2017 11:57:09 GMTtechnology@sc.edu of Fatigue Crack Generated Acoustic Emission Waveforms, 28 Jul 2017 10:02:36 GMTtechnology@sc.edu Scavenging from Broadband Ambient Vibration Using Sonic Crystal, 28 Jul 2017 08:44:07 GMTtechnology@sc.edu for Metal Remediation in the Environment, 21 Jul 2017 12:28:32 GMTtechnology@sc.edu Cell Energy Harvesting from Fluorescent Lights, 21 Jul 2017 09:17:03 GMTtechnology@sc.edu Black Hole ABH Sensor, 21 Jul 2017 08:26:36 GMTtechnology@sc.edu Sweating-Boosted Air Cooled Heat-Pipe Condensers, 21 Jul 2017 07:34:13 GMTtechnology@sc.edu Self-forming Membrane for High-flux and Selective Electrochemistry-based CO2 Capture, 18 Jul 2017 11:30:08 GMTtechnology@sc.edu of Metallocene-Containing Cationic Polymers for Anion Exchange Application, 07 Jul 2017 10:59:04 GMTtechnology@sc.edu Tunable Solar-Blind UV Detector Using EG/SiC Bipolar Photo-Transistor, 07 Jul 2017 10:42:52 GMTtechnology@sc.edu Device for Spinal Rod Contouring, 16 Jun 2017 13:12:41 GMTtechnology@sc.edu Grafted HIPE Foams for Chemical Separations, 12 Jun 2017 13:30:58 GMTtechnology@sc.edu of a Newly Discovered Pimarane Diterpenoid for Wound Healing, 12 Jun 2017 09:53:58 GMTtechnology@sc.edu of a Newly Discovered Abietane Diterpenoid for Cancer Treatment, 12 Jun 2017 09:51:51 GMTtechnology@sc.edu of a Newly Discovered Pimarane Diterpenoid for Cancer Treatment, 12 Jun 2017 09:20:16 GMTtechnology@sc.edu of a Newly Discovered Sesterterpenoid for Cancer Treatment, 12 Jun 2017 09:19:22 GMTtechnology@sc.edu With Extended Body Sounds Detection, 07 Jun 2017 12:07:17 GMTtechnology@sc.edu as Novel and Targetable Regulators of Angiogenesis, 12 May 2017 13:39:02 GMTtechnology@sc.edu Graphene Oxide Quantum Dots (N-GOQD) Thin Film Nanocomposite Reverse Osmosis Membranes for High Flux Desalination, 12 May 2017 08:59:07 GMTtechnology@sc.edu Line Directional System for 3D-Anatomy Ultrasound Phantom Trainer, 12 May 2017 08:51:12 GMTtechnology@sc.edu Resonator, 08 May 2017 13:06:37 GMTtechnology@sc.edu of Tissues Using Supercritical CO2, 05 May 2017 07:41:30 GMTtechnology@sc.edu of Smoking Gesture Using Smart Watches, 24 Apr 2017 10:24:55 GMTtechnology@sc.edu Pellet Die System, 24 Apr 2017 10:02:45 GMTtechnology@sc.edu CO2 Extraction of Residual Glutaraldehyde From Crosslinked Collagen, 21 Apr 2017 13:11:16 GMTtechnology@sc.edu Conjugated Nanogels in Microcapsule for Delayed Sustained Protein Delivery, 21 Apr 2017 11:13:20 GMTtechnology@sc.edu Structural Defect Geometric Features from Acoustic Emission Waveforms, 21 Apr 2017 07:52:51 GMTtechnology@sc.edu Connectors for Double Tee Beams, 21 Apr 2017 07:05:56 GMTtechnology@sc.edu Graphene Oxide (GO) Membranes for CO2 Separation, 21 Apr 2017 06:36:36 GMTtechnology@sc.edu for In Situ Zonal Regeneration of Articular Cartilage, 21 Apr 2017 06:12:01 GMTtechnology@sc.edu Inhibition of Aflatoxin Biosynthesis With Selected Silver Nanoparticles, 20 Apr 2017 14:39:40 GMTtechnology@sc.edu Plane Dislocations Elimination and Conversion Below the Epilayer Interface, 20 Apr 2017 14:37:43 GMTtechnology@sc.edu Three-Dimensional Cell Culture System, 20 Apr 2017 14:34:31 GMTtechnology@sc.edu Synthesis of High Quality Molybdenum Disulfide Thin Films, 20 Apr 2017 14:33:03 GMTtechnology@sc.edu Acid-Containing Compounds and Copolymers as Antimicrobial Agents, 20 Apr 2017 14:21:25 GMTtechnology@sc.edu Gene Expression Signature for Triple Negative Breast Cancer, 20 Apr 2017 14:03:04 GMTtechnology@sc.edu Mosquito Proteins to Create Dengue Virus Transmission-blocking Vaccines, 14 Apr 2017 09:52:11 GMTtechnology@sc.edu of Persistent Micelles, 06 Apr 2017 07:29:33 GMTtechnology@sc.edu Materials for the Prevention of Mild Traumatic Brain Injury, 17 Mar 2017 12:53:50 GMTtechnology@sc.edu G3BP Proteins to Accelerate Nerve Regeneration, 07 Mar 2017 13:17:16 GMTtechnology@sc.edu Tetragen Scintillators, 07 Mar 2017 11:45:04 GMTtechnology@sc.edu Deployment Method for Use of Nanotechnology for Oil Remediation, 10 Feb 2017 06:48:43 GMTtechnology@sc.edu Synthesis Of Hydrocarbons From Co-Electrolysis In Micro Tubular Reactor, 06 Feb 2017 13:07:52 GMTtechnology@sc.edu Cell Microsheets for Growth Factor Release and Immune Regulation, 06 Feb 2017 12:20:21 GMTtechnology@sc.edu Keratin-based Hydrogel for Cell Encapsulation, 06 Feb 2017 09:21:19 GMTtechnology@sc.edu Assessment of Damage During Manufacturing, 06 Feb 2017 08:49:03 GMTtechnology@sc.edu and Robust Porous Polymers Enabled by New Etch Chemistry, 27 Jan 2017 11:53:46 GMTtechnology@sc.edu Of Human Cancers In Peromyscus, 27 Jan 2017 11:41:47 GMTtechnology@sc.edu of Maleate and Maleimide Monomers and Polymers from Triglycerides, 25 Jan 2017 09:22:23 GMTtechnology@sc.edu Modulates Calcium Signaling in Rat Ventricular Myocytes: Possible Antiarrhythmic Properties, 25 Jan 2017 09:00:42 GMTtechnology@sc.edu Nanomaterials by Templating from Kinetically-trapped Polymer Micelles, 25 Jan 2017 08:57:49 GMTtechnology@sc.edu to Fabricate Micro-channel Array Structured Micro-tubular Solid Oxide Cells, 12 Dec 2016 13:06:54 GMTtechnology@sc.edu Switch for High Voltage DC Systems, 14 Sep 2016 09:22:58 GMTtechnology@sc.edu System for Improved Shingle Resistance to Separation, 13 Sep 2016 14:04:09 GMTtechnology@sc.edu Releasing Polymer Implants for the Treatment of Metabolic Disorders, 13 Sep 2016 13:53:18 GMTtechnology@sc.edu Scaled-up Nanotechnological Method for Separation of Oil/Water Mixtures using Flow-through Synthesis, 13 Sep 2016 13:49:12 GMTtechnology@sc.edu Test Protocols for SOFC Cathodes, 13 Sep 2016 13:35:38 GMTtechnology@sc.edu for Reforming Liquid Fuel to Tailor Engine Combustion-Emissions, 13 Sep 2016 13:29:36 GMTtechnology@sc.edu Channels as Non-Genomic Estrogen Targets for Overactive Bladder, 28 Jun 2016 08:46:59 GMTtechnology@sc.edu Estimation and Event Localization using Structural Vibrations #: 01180 The University of South Carolina is offering licensing opportunities for an algorithm for force estimation and localization of impacts to any structure. Invention Description: The subject invention enables location and force estimation of an impact anywhere within/on a structure (e.g. office building), using an algorithm that analyzes vibrations caused by an impact. Advantages and Benefits:The algorithm for FEEL (force estimation and event localization) offers a number of advantages including: Accurate estimation (99% confidence interval that force is within -2% +/- 1.3%) of...Tue, 28 Jun 2016 08:28:54 GMTtechnology@sc.edu of Thermoplastic Epoxidized Polymers and Thermosetting Materials from Triglycerides #: 01203The University of South Carolina is offering licensing for a method of preparation of thermoplastic epoxidized polymers and thermosetting materials from triglycerides. Background: Epoxidized soybean oils are commercially available and have been used as plasticizers in plastic industry. However, the preparation and application of epoxy resins from plant oils is still limited, due to the poor mechanical properties. This invention solves this problem detailing an alternative process/method for preparing epoxidized polymers. Invention Description:The subject invention is a simple...Tue, 28 Jun 2016 08:18:14 GMTtechnology@sc.edu of Self-Pulsing Regime of DC-driven Microplasma Discharge, 28 Jun 2016 08:10:44 GMTtechnology@sc.edu Generator: Carbon Gasification Assisted Solid Oxide Electrolysis Cell #: 01179 The University of South Carolina is offering licensing opportunities for a syngas generator that provides efficient and eco-friendly utilization of coal/biomass and CO2 to produce clean fuel and store energy. Invention Description: The subject invention is a carbon gasification (CG) assisted solid oxide electrolysis cell that can efficiently convert steam and carbon dioxide to syngas as a means of electricity storage and carbon dioxide utilization. This device also provides an eco-friendly and efficient way to use carbon-containing sources, such as coal and biomass, achievin...Tue, 28 Jun 2016 07:51:32 GMTtechnology@sc.edu Learning: Invention for Student Activities via Robotic Telepresence Interaction, 28 Jun 2016 07:37:47 GMTtechnology@sc.edu and Optimization of Lentiviral Vectors for CRISPR/Cas9 Delivery #: 01175 The University of South Carolina is offering licensing opportunities for an all-in-one CRISPR/Cas9 delivery platform with significant upregulation in vector production efficiency and gene expression. Invention Description: The subject invention is a delivery platform for use in gene editing that includes a relatively short, highly efficient promoter that drives transcription of a nucleic acid sequence that encodes a gene-editing molecule, e.g., either a gRNA or a nuclease. In conjunction with this promoter, the vector includes one or more transcription factor binding eleme...Sun, 26 Jun 2016 18:17:50 GMTtechnology@sc.edu Displacement Sensing System Utilizing Edge Diffraction, 26 Jun 2016 18:09:42 GMTtechnology@sc.edu labeled three layer core-shell nanoparticles #: 01100 The University of South Carolina is offering licensing opportunities for novel isotopically-enriched core-shell nanoparticles to quantify the respective roles of the particle and the ion from particle dissolution in bioaccumulation. Invention Description: Nanoparticles of between 10-50 nm in size can be made of pure metals or their oxides, alloys of two more metals (or oxides) or as core-shell nanoparticles. In this case, there are two layers of metals (or their oxides) which are pure phases of that component in each layer. The subject invention uses three layers and labels ...Sun, 26 Jun 2016 17:59:50 GMTtechnology@sc.edu Reproducible Sample Preparation Method for Quantitative Stain Detection #: 01146The University of South Carolina is offering licensing opportunities for a method that allows liquid stains to be created on fabric in a reproducible and constant manner that greatly reduces unwanted variability between samples of different dilution or fabric type.Invention Description: The subject invention is a stain-barrier that can be easily applied to fabric samples to limit the amount of fabric with which the deposited liquid is able to interact. This stain barrier greatly reduces unwanted variability between samples of different dilution or fabric type so that limits o...Sun, 26 Jun 2016 15:32:10 GMTtechnology@sc.edu Enhances the Efficacy of Dendritic Cell Vaccine for Cancer #: 01197The University of South Carolina is offering licensing opportunities for nanoparticle delivery tools (microRNA transfection) that enhance the efficacy of dendritic cell vaccines for cancer.Background:In anti-tumor immunity, dendritic cells (DCs) capture, process, and present tumor antigens to T cells, initiating a tumoricidal response. However, DCs are often dysfunctional due to their exposure to the tumor microenvironment (TME) as a result, dendritic cell vaccines developed for many cancers including breast cancer as immunotherapies have been ineffective. However, microRNA-1...Sun, 26 Jun 2016 15:23:48 GMTtechnology@sc.edu Substrate Analogue Inhibitors of Ribose 5-Phosphate Isomerase, 26 Jun 2016 15:04:18 GMTtechnology@sc.edu Core-shell Particles as Effective Vaccine Delivery Vehicles #: 01168The University of South Carolina is offering licensing opportunities for a method to formulate protein-based antigens, especially glycoproteins-based antigens that enhance in vivo immune responses.Invention Description:The subject invention describes a novel vaccine delivery system using a self-assembled nanoparticle system. Protein-based antigens self assemble with proprietary, biocompatible polymers to form core-shell nanoparticles. Such nanoassemblies can induce much stronger immune responses as observed from in vivo studies.Potential Applications:Vaccine development...Sun, 26 Jun 2016 13:47:02 GMTtechnology@sc.edu and Steering in Plate-Like Anisotropic Structures #: 01166The University of South Carolina is offering licensing opportunities for a phased array technique to rapidly inspect damage in large composite structures. It may be used to assess the quality of composites in product design and manufacturing processes.Invention Description:The subject invention describes a phased array technique that allows rapid inspection of large areas of composite material. Compared to the traditional methods, which are designed for isotropic metallic structures, this invention offers a revolutionary approach for rapid damage inspection in composites. It...Sun, 26 Jun 2016 13:36:32 GMTtechnology@sc.edu of Fiber Reinforced Engineering Thermoplastic Filament for 3D Printing #: 01164 The University of South Carolina is offering licensing opportunities for fiber reinforced thermoplastic parts composed of continuous filament. Invention Description: The subject invention allows the controlled manufacture of continuous fiber reinforced plastic filament. This filament can be used in combination with a dedicated 3D printer to print continuous fiber reinforced parts which are superior to the unreinforced plastic parts printed with the current generation of 3D printers. Advantages and Benefits: Current printers allow printing of continuous fiber polymer but so f...Sun, 26 Jun 2016 12:40:31 GMTtechnology@sc.edu Robotic 3D Printing System for (Fiber Reinforced) Polymer Parts #: 01157 The University of South Carolina is offering licensing opportunities for an integrated 3D printing system to multi-axial composite parts. Invention Description: The subject invention is a 3D printer that can print thin composite parts with continuous fibers in multiple directions. The printer allows the production of thin-walled, carbon fiber-reinforced parts without the use of positive or negative molds. It combines the advantages of traditional 3D printing with plastics with the strength and stiffness of composite parts produced with methods such as vacuum injection. Pot...Sun, 26 Jun 2016 12:14:45 GMTtechnology@sc.edu Sample Preparation Using 3D Printing #: 01152 The University of South Carolina is offering licensing opportunities a method of 3D printing polymer boundaries that allows fast preparation of reproducible sampling areas on the fabric substrate sample materials while minimizing variability. Invention Description: The subject invention is a reproducible sample preparation method for 3D printed polymer rings that provide boundaries on different fabric types to hold liquid samples up to 500 uL. This allows liquid samples with different dilutions to spread uniformly within the same area. In addition, the rings also differe...Sun, 26 Jun 2016 11:51:52 GMTtechnology@sc.edu PSA Screening for Virulent Prostate Cancer, 12 Feb 2016 12:30:31 GMTtechnology@sc.edu Cancer Stem Cells By Metformin To Treat Malignant Neuroblastoma #: 01167 The University of South Carolina is offering licensing opportunities for a metformin-based drug formulation (alone or in combination with other existing drugs) to inhibit cancer metastasis and treat pediatric cancers such as neuroblastoma.Invention Description: The subject invention utilizes metformin to induce apoptotic cell death in neuroblastoma stem cells that cause tumor growth. It also inhibits the self-renewal and differentiation potential of new neuroblastoma stem cells to prevent the further occurrence and progression.Advantages and Benefits: Metformin is cost effec...Mon, 07 Dec 2015 11:59:32 GMTtechnology@sc.edu Coated PLGA Nanoparticle for Photothermal Therapy #: 01169 The University of South Carolina is offering licensing opportunities for a biodegradable, photothermal-responsive nanoparticle that can be used for disease therapy, drug delivery, and other biomedical applications.Invention Description: The subject invention is a dual-functional, photothermal nanoparticle that not only delivers therapeutic agents to a target within the body but also generates heat under exposure to near-infrared (NIR) irradiation. The hybrid nanoparticle uses FDA-approved materials and includes a poly(lactic-co-glycolic acid) (PLGA) core and a polydopamine s...Thu, 19 Nov 2015 14:12:26 GMTtechnology@sc.edu Nanofiltration Membranes Prepared by Molecular Layer Deposition, 19 Nov 2015 13:30:22 GMTtechnology@sc.edu Activity of Ciclopirox #: 01154 The University of South Carolina is offering licensing opportunities for using Ciclopirox to treat diabetes and other conditions that involve the loss of glucose homeostasis.Invention Description: The subject invention is a novel use of Ciclopirox (also known as CPX, Loprox, or Ciclodan), an antibiotic used for fungal infections, to modulate glucose homeostasis, thereby regulating blood sugar levels that are responsible for many symptoms associated with diabetes. Potential Applications: CPX may be used for the treatment of diabetes, including but not limited to type I diabet...Thu, 19 Nov 2015 08:23:59 GMTtechnology@sc.edu Therapy for Metastatic Breast Cancer #: 01150 The University of South Carolina is offering licensing opportunities for a novel therapy that slows breast cancer metastasis by interfering with Ccl8, a protein instrumental to cancer cell dissemination.Invention Description: The subject invention identifies the cytokine Ccl8 as a protein that is released by the stromal cells in response to signals produced by cancer cells, especially breast cancers that are triple negative (i.e Her2-, ER-, and PR-). Disrupting Ccl8 activity inhibits cancer cell migration thus providing a strategy to inhibit breast cancer metastasis. Potenti...Thu, 19 Nov 2015 07:02:37 GMTtechnology@sc.edu Preparation of Brain Targeted Nanoparticle and its Application, 22 Jul 2015 06:27:01 GMTtechnology@sc.edu Perfusion Bioreactor Mimics, Controls, and Optimizes Blood Vessel Mechanics, 22 Jul 2015 06:20:31 GMTtechnology@sc.edu Switched Graphene/4H-SiC Junction Bipolar Transistor (G-SiC BJT), 04 Jun 2015 12:25:04 GMTtechnology@sc.edu Preparation of Polymeric Prodrug of Disulfiram and its Application, 20 Jan 2015 13:33:37 GMTtechnology@sc.edu Inhibitors of Hexokinase and Glucokinase, 16 Jan 2015 11:48:26 GMTtechnology@sc.edu Barrier Detection Devices Having a 4H-SiC n-Type Epitaxial Layer, 13 Jan 2015 12:20:06 GMTtechnology@sc.edu of Alkali-Silica Reaction in Concrete, 13 Jan 2015 11:03:20 GMTtechnology@sc.edu Microcantilever-Based Selective Volatile Organic Compound (VOC) Sensor, 12 Jan 2015 07:57:43 GMTtechnology@sc.edu, Bimetallic Nanoparticles for Selective Catalysis, 06 Jan 2015 07:48:07 GMTtechnology@sc.edu Of Chemicals, Monomers And Polymeric Materials From Triglycerides, 17 Dec 2014 09:01:40 GMTtechnology@sc.edu Copolymer Systems as Templates for Block Copolymer Nanolithography, 16 Dec 2014 11:43:02 GMTtechnology@sc.edu Of Conjugated Aromatic/Heteroaromatic Oligomer-Containing Dielectric Polymers And Their Applications, 16 Dec 2014 11:42:52 GMTtechnology@sc.edu Piezoelectric Fabrication of 3D Structures, 12 Dec 2014 09:13:36 GMTtechnology@sc.edu Nanobubble Generation and Flows Enabled by Novel Superhydrophilic Bi-porous Interfaces, 11 Dec 2014 11:22:32 GMTtechnology@sc.edu of Polyvinylpyrrolidone Grafted Nanoparticles using New RAFT Agent, 02 Dec 2014 13:29:16 GMTtechnology@sc.edu Microtubular Laminated Composite Scaffold Composition, 02 Dec 2014 13:29:12 GMTtechnology@sc.edu of Facial and/or Ocular Infection Avoidance, 24 Nov 2014 14:04:46 GMTtechnology@sc.edu Combination for Cancer Targeted Therapy, 24 Nov 2014 10:43:46 GMTtechnology@sc.edu Novel Method of Preparing Lipamino Acids and Lipopeptides, 20 Nov 2014 14:20:13 GMTtechnology@sc.edu and Highly Repeatable Fabrication of Low Cost, Ultrathin Graphene Oxide Membranes for Highly Selective Gas Separation, 19 Nov 2014 12:49:58 GMTtechnology@sc.edu of Gold/Silica Hybrid Nanoparticle and Its Applications, 10 Nov 2014 13:14:34 GMTtechnology@sc.edu High-Gain MIMO Antenna Array for Handheld Wireless Terminals, 21 Oct 2014 14:00:09 GMTtechnology@sc.edu Restoration by Resuspension of Sediment by Hydraulic Jet, 20 Oct 2014 14:11:11 GMTtechnology@sc.edu Lithium Ion Battery Electrode and Methods for Fabricating Such #: 01088 The University of South Carolina is offering licensing opportunities a single-step approach for synthesizing novel electrodes for lithium ion batteries in large quantities.Invention Description: The subject invention is a facile and scalable process to synthesize bulk electrodes for lithium ion batteries. These electrodes exhibit superior electrochemical properties and provide an ideal structure for lithium ion batteries that results in high power density, capacity retention, and overall improved performance.Potential Applications: Developing cost-effective anode materials f...Mon, 20 Oct 2014 14:11:09 GMTtechnology@sc.edu of an Iron Analog of a Zeolite #: 01101 The University of South Carolina is offering licensing opportunities for a new class of complete iron-based, zeolite analogs with three-dimensional frameworks.Invention Description:The subject invention represents the first examples of a zeolitic iron framework structure. These synthesized crystals are complete iron analogs of the basic zeolite known as sodalite. The presence of the transition element iron introduces electronic and magnetic properties to the iron-based zeolite crystal structure since the tetrahedral sites are all occupied by iron rather than by aluminum or s...Tue, 30 Sep 2014 14:07:33 GMTtechnology@sc.edu of Operating Hydrogen Pumps with High-Concentration Hydrogen Sulfides, 07 Aug 2014 13:24:35 GMTtechnology@sc.edu Oxidation of Methane (POM) Assisted Solid Oxide Electrolysis, 07 Aug 2014 13:08:01 GMTtechnology@sc.edu Functionalized Nanoparticles for Quenching Bacterial Communications, 05 Aug 2014 11:09:55 GMTtechnology@sc.edu Novel Chemically Stable Ceramic-Metal Composite Membrane For Hydrogen Separation, 05 Aug 2014 10:07:05 GMTtechnology@sc.edu Technology for One-Step Upgrading of Biomass-Derived Chemicals #: 01019 The University of South Carolina is offering licensing opportunities for novel catalyst technology for biofuel production.Invention Description: The subject invention is a catalyst technology that combines the traditional method of removing oxygen from carbohydrates required for liquid fuels and the traditional method for forming long-chain molecules present in gasoline and diesel fuels into a single process that does not require liquid phase operations.Potential Applications: Biofuel production (e.g. liquid carbon production)Advantages and Benefits: 1. Scalable, single step...Mon, 14 Jul 2014 09:19:04 GMTtechnology@sc.edu of Supercritical CO2 with Water for Decellularization of Matrices, 07 Jul 2014 14:25:01 GMTtechnology@sc.edu Alkyl (Meth)Acrylates Grafted Nanoparticles and Their Methods of Manufacture and Use #: 01068 The University of South Carolina is offering licensing opportunities for a method of functionalizing nanoparticles with polyolefin-like polymers and dispersing them in polyolefins.Invention Description:The subject invention is a method of grafting polyolefin-like poly(meth)acrylates on inorganic nanoparticles in a controlled manner. This invention demonstrates further how to mix the poly alkyl (meth)acrylates-grafted nanoparticles with polyolefins like polyethylene and polypropylene to create nanocomposites with good dispersion.Potential Applications:Packaging and plastics s...Mon, 07 Jul 2014 14:15:38 GMTtechnology@sc.edu Grafted Nanoparticles, 07 Jul 2014 14:06:19 GMTtechnology@sc.edu Two-phase Evaporators/Boilers Enabled by Nano-tip-Induced Boundary Layers, 07 Jul 2014 13:58:59 GMTtechnology@sc.edu Acoustic Contrast Tomography for Studying Fungal Growth and Toxicity #: 01080 The University of South Carolina is offering licensing opportunities for a minimally invasive technique that can provide accurate information of the mechanical and the morphological features of an entire landscape of an expanding fungal colony.Invention Description:The subject invention is can simultaneously study the structural, architectural, and material properties as well as the mechanical strength properties in a fungal colony. This can be used to predict levels of fungal invasion and toxicity under a given set of environmental conditions. The technology consists of a t...Mon, 07 Jul 2014 11:56:44 GMTtechnology@sc.edu of Platform Chemicals to Liquefied Petroleum Gas (LPG), 07 Jul 2014 11:38:17 GMTtechnology@sc.edu Preparation of Triple Responsive Nanogel System and its Application, 07 Jul 2014 10:37:44 GMTtechnology@sc.edu CATIONIC COMPOUNDS AND POLYMERS LOADED WITH ANTIBIOTICS AS ANTIMICROBIAL AGENTS Reference #: 01060 The University of South Carolina is offering licensing opportunities for this novel method of utilizing systems to target drug resistant bacteria. Invention Description: The present invention uses cationic metallocene derivatives to promote the effects of traditional antibiotics against a broad spectrum of bacterial pathogens including drug resistant bacteria. These materials have excellent effects against Gram-negative and Gram-positive bacteria, including various kinds of multidrug-resistant bacteria including Staphylococcus, Enterobacteriaceae, Haemophilus influenzae, N...Thu, 02 Jan 2014 08:38:51 GMTtechnology@sc.edu as a Therapy for Metastatic Cancers, 19 Dec 2013 12:46:34 GMTtechnology@sc.edu ENCLOSURE FOR HANDHELD DEVICES, 04 Dec 2013 07:41:15 GMTtechnology@sc.edu B in Neuroblastoma Treatment, 01 Nov 2013 08:20:59 GMTtechnology@sc.edu Sounds to Simulated Ultrasound Examinations, 01 Nov 2013 08:12:41 GMTtechnology@sc.edu Loop Control, 01 Nov 2013 08:04:42 GMTtechnology@sc.edu of Magnetic Nanoparticles, 28 Oct 2013 12:13:04 GMTtechnology@sc.edu Frequency Microbubble-switched Oscillations Modulated by Microfluidic Transistors, 28 Oct 2013 12:09:27 GMTtechnology@sc.edu miRNAs as Biomarkers for Endometriosis, 28 Oct 2013 11:48:05 GMTtechnology@sc.edu Phosphonate/Phosphonic Acid RAFT Agents and Monomer Design, 21 Oct 2013 07:29:34 GMTtechnology@sc.edu Algorithm for Protection Circuit for DC Power Distribution Systems, 30 Sep 2013 11:40:39 GMTtechnology@sc.edu of Growing High Quality Epitaxial Graphene with Thickness Controllability #:  01008The University of South Carolina is offering licensing opportunities for a method of achieving thin to thick graphene from a few monolayers to several microns with excellent surface morphology and uniformity, the combination of which is not realizable by other techniques.Invention Description:The subject invention is a novel method of growing epitaxial graphene by changing the silicon loss mechanism necessary for subsequent C-rich layers to form. This allows thickness and electronic properties to be controlled simultaneously, breaking the fundamental trade-off between crysta...Mon, 30 Sep 2013 10:32:33 GMTtechnology@sc.edu of Nanogel Cocktail and its Application, 27 Sep 2013 07:33:52 GMTtechnology@sc.edu Automated ISFET-Based Ion Channel Screening System, 20 Sep 2013 11:41:35 GMTtechnology@sc.edu of Colloidal Nanocrystals by Gel Permeation Chromatography, 20 Sep 2013 11:40:00 GMTtechnology@sc.edu Imaging of Chemical Contrast via Differential Heating, 06 Aug 2013 12:07:32 GMTtechnology@sc.edu Cationic Metallocene-containing Compounds and Polymers as Antimicrobial Agents Reference #: 01016 The University of South Carolina is offering licensing opportunities for new types of cationic organometallic compounds and metal-containing polymers, or "metallopolymers," for drug-resistant, antimicrobial applications. Invention Description: The subject invention demonstrates the utilization of cationic metallocene moeities that exhibit antimicrobial properties when paired with a variety of different anions. These organometallic molecules and their charged metallopolymers inhibit a broad spectrum of pathogens, including Gram-positive and Gram-negative bacteria and many ki...Thu, 25 Jul 2013 09:17:47 GMTtechnology@sc.edu Sanitizing Device Reference #: 01009 The University of South Carolina is offering licensing opportunities for devices that automatically sanitize switch surfaces using UV germicidal radiation to prevent transfer of communicable diseases from contaminated switch surfaces. Invention Description: The present invention addresses the need for sanitization or decontamination of the contact areas of manual switches by providing a localized source of germicidal electromagnetic radiation that is directed toward said contact surfaces via novel routing and shielding of said radiation. The device is designed in such a wa...Thu, 20 Jun 2013 12:09:09 GMTtechnology@sc.edu Catalysts for Oxidative Environments #: 01031The University of South Carolina is offering licensing opportunities for a method of synthesizing self-healing catalysts that eliminate the need for periodic regeneration caused by catalyst deactivation.Invention Description:The subject invention achieves self-healing functionality by carefully controlling crystallographic facets exposed on the active catalyst surface to promote the reduction of oxidized species that cause deactivation.Potential Applications:Extending catalyst lifetimes in many catalytic reactions, such as CO2 mitigation and biomass upgrading, during which wa...Thu, 20 Jun 2013 12:09:06 GMTtechnology@sc.edu Glucose Sensing Fluid for Continuous Glucose Monitoring Reference #: 00685 The University of South Carolina is offering licensing opportunities for a new system for continuing glucose monitoring. This technology helps to treat and control diabetes and its serious complications, which can lead to premature. Potential Applications: The system can be used as part of the successful treatment and control of diabetes. Advantages and Benefits: Provides for continuous monitoring of blood glucose levels Uses a stable, biocompatible sensing fluid in a previously developed microelectromechanical system Provides accurate and highly specific response i...Tue, 19 Mar 2013 16:37:49 GMTtechnology@sc.edu Cell-free Assay for Detection of Quorum Sensing Signals, Acyl-Homoserine Lactones (AHLs), 19 Mar 2013 10:51:52 GMTtechnology@sc.edu and Apparatus for Online and Selective Measurement of Gas Permeation Through Polymer Films, 18 Mar 2013 13:00:19 GMTtechnology@sc.edu Infant and Toddler Environments (chapters 5-15) Reference # 00852 The University of South Carolina is offering licensing opportunities for this technology. Potential Applications: BASICspaces improves the quality of spaces where children grow, learn, and play. Advantages and Benefits: BASICspaces has already improved the quality of over 80 child care centers in South Carolina. Invention Description: BASICspaces is a three-pronged early care and education intervention program that improves the quality of spaces where children grow, learn, and play. The project, which stands for Building Academic Success in Childhood Spaces, is grounded in ...Tue, 12 Mar 2013 13:00:42 GMTtechnology@sc.edu Handle, 05 Feb 2013 09:33:39 GMTtechnology@sc.edu Barrier for Ultrasound-guided Procedures #: 00987Background:Frequently, ultrasound procedure kits are used for sterility purposes to prevent infection when skin puncture is necessary for ultrasound guided procedures. These kits can include a sterile ultrasound probe cover, sterile gel, and drape, but are expensive and time consuming to use. Ultrasound trained practitioners who routinely perform procedures such as removing fluid from the lungs or an arthritis joint or placing medicine into a joint need to have some way to prevent contamination of the sterile area of the skin puncture site to prevent infection. Instead of usi...Tue, 05 Feb 2013 09:33:39 GMTtechnology@sc.edu Based Nanocomposites Including Inorganic Nanoparticles and Their Methods of Manufacture and Use Reference #: 00992 Background: Compared with pure silicone polymer, silicone-based nanocomposites can realize enhanced mechanical, thermal, electric, dielectric and optical properties by adding functional inorganic nanofillers. However, the incompatibility between inorganic nanofillers and an organic matrix normally leads to large agglomerates of the inorganic nanofillers within the polymer matrix. The agglomeration leads to a loss in optical transparency and severely limits the use of these materials in optical applications. This is especially true for silicone nanocomposites because the sur...Tue, 05 Feb 2013 09:33:37 GMTtechnology@sc.edu Polymeric Additive for Strength and Deformability Enhancement of Cementitious Composites, 25 Jan 2013 13:18:38 GMTtechnology@sc.edu Method for Synthesis of Xanthones and Sparstolonin B (SsnB) Derivatives Reference #: 00989 Invention Description: The subject invention is a novel one-step, high yielding ortho-acylation reaction of phenols capable of synthesizing xanthones under considerably mild conditions. Background: Xanthones are important structural units in organic chemistry and widely present in natural products. Their derivatives show diverse physicochemical and pharmacological properties including antioxidant, anti-inflammatory, antibacterial, antineoplastic, and vasodilator. Furthermore, xanthones are important intermediates for synthesizing Sparstolonin B (SsnB), an effective anti...Thu, 10 Jan 2013 12:10:31 GMTtechnology@sc.edu of Plant Virus Particles and Polymers as 2D and 3D Scaffolds to Manipulate Cellular Behaviors, 10 Jan 2013 12:10:30 GMTtechnology@sc.edu of Loss Analysis and Mapping of Coastal Wetland Habitat, 26 Nov 2012 14:33:38 GMTtechnology@sc.edu of Degradable Salt-Responsive Copolymers Reference #: 00974 Invention Description: The subject invention is a method of making salt-responsive, water-dispersible, 100% biodegradable, cationic co-polymers and their applicability as binder compositions. The invention provides an entirely new approach to develop new binder compositions for personal care products such as baby diapers, incontinence products, tissues and wet wipes, and feminine hygiene products. Successful implementation of these polymers will enable replacement of some non-degradable acrylic polymers used as the standard today. Advantages and Benefits: The copolymers ha...Tue, 20 Nov 2012 11:45:43 GMTtechnology@sc.edu and Apparatus for Improved Mixing of Solid, Liquid or Gaseous Material and Combinations Thereof, 13 Nov 2012 09:40:22 GMTtechnology@sc.edu Nitride Microcantilever based Photoacoustic Biosensor #: 00978 The University of South Carolina is offering licensing opportunities for this novel biosensor for use in detecting cancer cells in blood samples.Invention Description:The subject invention is a highly sensitive and miniaturized biochip sensor capable of detecting a single melanoma cancer cell in circulating blood samples. The pre-clinical and clinical applications in detecting cancer metastasis and prognosis are extensive. The biochip sensor utilizes the photo-acoustic detection technique to differentiate cancer cells from other cells present in blood in a label-free manner,...Wed, 31 Oct 2012 08:01:58 GMTtechnology@sc.edu Nitride Microcantilever based Nuclear and Radiological Sensor #: 00979The University of South Carolina is offering licensing opportunities for this novel, cost-effective system used in identifying radioactive fission gasses.Invention Description:The subject invention is a portable sensor system developed for identifying radioactive fission gases. It addresses the drawbacks of current state-of-the-art systems and facilitates easy and widespread monitoring for safe and clean nuclear operations. The detection of radioactive fission gases, 129I, 133Xe, and 85Kr, involves utilizing the high sensitivity and versatile detection capability of radiation...Wed, 31 Oct 2012 07:40:59 GMTtechnology@sc.edu Reactor for Hydrogen Production Reference #: 00677 Invention Description: This technology deals with the production of hydrogen using hydrides. It is a method and reactor configuration for treating a chemical hydride with water at an elevated temperature to cause a reaction (hydrolysis) between the hydride and the water to produce hydrogen. The technology is also a novel method for delivering a hydride to a reaction zone in a manner that allows rapid reaction of a hydride with water to produce hydrogen. Advantages and Benefits: This technology does not require acid or a heterogeneous catalyst for hydrolysis to occur. It p...Tue, 30 Oct 2012 13:31:33 GMTtechnology@sc.edu Inflammatory Index Reference#: 00984 Invention Description: The subject invention is a Dietary Inflammatory Index. The DII is a new tool for assessing the inflammatory potential of diet that can be applied to any population in which dietary data have been collected. It also has the potential to be used for evaluating and guiding individuals in setting dietary goals to decrease levels of inflammation and possibly reduce the risk of certain chronic conditions. Advantages and Benefits: Even though other dietary indices exist, this invention is the first known literature-based index to focus primarily on the inf...Wed, 24 Oct 2012 10:42:14 GMTtechnology@sc.edu Reclosing Method for Service Restoration in a Power System Reference#: 00976 Invention Description: This invention is a process for using inverter-coupled local energy storage to softly restart an industrial power network after a grid outage. The soft restart process eliminates a number of problems commonly associated with simply reclosing a circuit breaker -- problems such as large inrush currents, motor torque pulsations, and voltage dips on the power line feeding the plant. The soft restart process applies a specific protocol to pre-energize or rapidly re-energize the network while still in islanded mode, and then to reclose the circuit breaker on...Fri, 12 Oct 2012 12:46:01 GMTtechnology@sc.edu Tools and Diagnostics: Novel Peptide-Based Borono-Lectin (PBLs) Sugar Sensors, 18 Sep 2012 15:45:53 GMTtechnology@sc.edu Spintronic Chemical Sensor, 18 Sep 2012 15:45:44 GMTtechnology@sc.edu Electrocatalyst Support and Catalyst Supported Thereon, 18 Sep 2012 14:31:27 GMTtechnology@sc.edu Gene Delivery System for Gene Therapy and Methods of Its Use, 18 Sep 2012 14:31:26 GMTtechnology@sc.edu and Systems for Determining Entropy Metrics for Networks Reference #: 00546 Invention Description: The subject invention is a method for the reduction of large network connection matrices to far less numbers of variables, thus constituting an invention of new "entropy matrices for the network". Potential Applications: The use of such intellectual property or technology is for the classification and tracking of the behavior of complex systems over time to identify failures, attacks, major structural changes in the topology, and other variance within Internet Networks. Advantages and Benefits: Reduction of large networks to a few representative param...Tue, 18 Sep 2012 14:31:25 GMTtechnology@sc.edu Electrolytic Production of Hydrogen Reference #: 00482 Invention Description: The hydrogen economy is viewed by many as the world's long-term solution to our energy needs. An example of how hydrogen would be used in this new economy is via proton exchange membrane (PEM) fuel cells. PEM fuel cells operating on pure hydrogen have excellent energy and power capabilities. However, producing pure hydrogen from water using electrolysis is not economical. This invention involves a new process for combining electrolysis and thermal chemistry to economically produce hydrogen. Advantages and Benefits: The current production of hydrogen ...Tue, 18 Sep 2012 14:31:24 GMTtechnology@sc.edu and Integrated Circuit Implementation of a Driver Circuit for GaN HFETs, 18 Sep 2012 06:27:34 GMTtechnology@sc.edu as NO2 Sensor Using Surface Work Function Changes Reference #: 00645 Invention Description: This invention is a novel sensor based on electromechanical principles using a resonant microcantilever. It can be used for detecting volatile chemicals, toxic gases, and bio-agents. The technology is based on a highly economical film deposition technique on a substrate (as opposed to the cantilever that is normally used) to create a surface that is highly sensitive and selective to various target gases. Potential Applications: This invention will be used for toxic gas sensing, pollution control, bio-hazard detection, and counter terrorism/homeland ...Tue, 18 Sep 2012 06:27:34 GMTtechnology@sc.edu Composition for Repairing Skeletal Tissue #:  00504The University of South Carolina is offering licensing opportunities for the development of novel macromers used for tissue regeneration.Invention Description:This invention involves the development of novel PLA, PGA and PLGA macromers. These macromers can be formed into a paste and are able to conform to the shape of irregular defects or made into viscous liquid compositions for injection into defects in minimally invasive procedures. The invention also features the addition of unsaturated reactive groups to the short polymer chains for in situ crosslink-ability.Advantages ...Tue, 18 Sep 2012 06:27:34 GMTtechnology@sc.edu of a Highly Crystalline, Covalently Linked Porous Network, 18 Sep 2012 06:27:33 GMTtechnology@sc.edu Novel Screen of PAD4 Inhibitors Reference #: 00689 Invention Description: The subject invention is an Activity-Based Protein Profiling (ABPP) assay in which a potential inhibitor compound competes with rhodamine-conjugated fluoroamidine to bind to PAD4. Fluorescence is measured to determine an estimate of the amount of fluorescent protein arginine deiminase 4 that is present in the assay. Potenttial Applications: Protein Arginine Deiminase 4 (PAD4) is a leading target for the development of a Rheumatoid Arthritis (RA) pharmaceutical. Advantages and Benefits: Overcomes the limitations of commonly used PAD4 assays by elimi...Tue, 18 Sep 2012 06:27:33 GMTtechnology@sc.edu Resistance) - A Method of Enhancing Systemic Acquired Resistance in Plants #:  00194The University of South Carolina is offering licensing opportunities for this method of generating tobacco plants that are less susceptible infection.Invention Description:This invention specifically provides an alternate use for the booster sequence in tobacco plants.  The use of the booster sequence will suppress the immune system (post transcriptional gene silencing) but its supplication to plant material also induces general and induced resistance to plant pathogens such as viruses or fungi.  (P1/HC-Pro lines have an enhanced Systemic Acquired Resistance response.)  In o...Tue, 18 Sep 2012 06:27:33 GMTtechnology@sc.edu endogenous regulator of RNA silencing in plants Reference #: 00454 Invention Description: The subject technology is a technique or method for altering gene expression in plants by regulating an endogenous mechanism called RNA silencing (or RNA interference-RNAi). A certain transcription factor was discovered which, when overexpressed, delays the onset of RNA silencing, thus allowing longer expression of the silenced gene. Conversely, when the expression of this same transcription factor is decreased by various means, the plants silence more rapidly and more effectively. This invention includes the identification of a tobacco protein (terme...Tue, 18 Sep 2012 06:27:32 GMTtechnology@sc.edu for Treating Osteoarthritis and Enhancing Wound Healing, Tissue Engineering and Stem Cell Research, 18 Sep 2012 06:27:31 GMTtechnology@sc.edu Method and Apparatus for Slicing Hard, Brittle Materials, 18 Sep 2012 06:27:30 GMTtechnology@sc.edu Structural Radar (EUSR) with Piezoelectric Wafer Active Sensors (PWAS) for Wide-Area Nondestructive Evaluation of Thin-Wall Structures, 18 Sep 2012 06:27:30 GMTtechnology@sc.edu Integrated Detection and Analysis System (MIDAS) #: 00681Invention Description:The present invention is a novel Multidimensional Integrated Detection and Analysis System (MIDAS) which leads to the development of robust, versatile, and inexpensive sensors based on a nano-structured graphite and/or Graphene functionalization layer that can be put very easily and economically on a variety of substrates. The system uniquely integrates potentiometric and capacitive detection techniques with the commonly used amperometric technique for highly sensitive, expedient, and accurate detection of target molecules.Advantages and Benefits:Traditi...Tue, 18 Sep 2012 06:27:30 GMTtechnology@sc.edu Approach to Localized Electric Field Application and Harvesting Within a Continuous Medium, 18 Sep 2012 06:27:29 GMTtechnology@sc.edu Storage from Cellulose Fiber Materials, 11 Sep 2012 07:12:01 GMTtechnology@sc.edu of Making Homogeneously Porous Solid Matrix with Tunable Porosity and Pore Size, 04 Sep 2012 11:18:17 GMTtechnology@sc.edu to Reverse Engineer Computer Application Screens, 04 Sep 2012 08:17:57 GMTtechnology@sc.edu Primers for Improved Detection of Vibrio Parahaemolyticus Thermostable Direct Hemolysin (TDH) and TDH-related Hemolysin (TRH) Genes 00977Invention Description:The subject invention involves two new sets of PCR primers for the detection of the thermostable direct hemolysin (tdh) and TDH-related hemolysin (trh) genes. Analysis using these new primers detected 28 tdh positive and 5 trh positive strains in a collection of 68 environmental Vibrio isolates. The identities of all PCR products were confirmed by DNA sequence analysis. Screening the same set of isolates with previously described sets of primers (Bej, A.K., D.P. Patterson, C.W. Basher, M.C.L Vickery, D.D Jones and C.A Kaysner. 1999. J. Microbiol. Methods 3...Tue, 04 Sep 2012 08:17:53 GMTtechnology@sc.edu Stereo Calibration System and Method for Accurate Digital Image Correlation Measurements #: 00612The University of South Carolina is licensing a stereo calibration method for accurate digital image measurements in multi-media applications. This method allows users to employ standard optical equipment to measure accurately the motion and strain of an object immersed in a medium that is different from the one in which the measurement equipment is located. The method can be used with a variety of measurement systems and interfaces.Problem:It is difficult to measure motion and strain accurately for objects that are immersed in a medium that is different from the medium in wh...Wed, 22 Aug 2012 13:21:36 GMTtechnology@sc.edu Secured Therapeutic Peptide Delivery System for Cancer Therapy, 21 Aug 2012 13:53:34 GMTtechnology@sc.edu Sensors for Infrastructure Monitoring Reference #: 00789 Background: Smart sensors have the capability to communicate with other sensors and process information locally using their own wireless units and microprocessor. Smart sensor hardware has already been developed by other researchers and their capacities have been tested in real civil structures (Nagayama and Spencer, 2007; Lynch et al., 2004). Even though these studies have shown potential in substantially reducing the time and cost of instrumenting a structure, there are still some fundamental challenges faced by this technology such as battery life and overload of the com...Tue, 21 Aug 2012 07:11:04 GMTtechnology@sc.edu Bacteriophage as a Chemoaddressable Nanoparticle for Sensing and Cell Culturing #: 00749Invention Description:The present invention is the use of M13 bacteriophage for cell targeting, cell imaging, drug delivery vehicle, and bio-scaffold able to direct cell growth.Potential Applications:Can be customized for various therapeutic applications: bio-imaging (use of fluorescent dyes, magnetic contrast imaging agents) cell targeting molecules (use of boronic acids, folic acid, antibodies) drugs at high local concentrations to increase detection sensitivity and efficacy for therapeutic applications Advantages and Benefits:Provides a wide array of shapes as rods and ...Tue, 21 Aug 2012 07:11:01 GMTtechnology@sc.edu<![CDATA[Improved Method for Industrial Scale Micropropagation of Select Monocots (Arundo, Miscanthus & Scirpus) based on Sustained Totipotent Cell Cultures]]>, 16 Aug 2012 14:19:45 GMTtechnology@sc.edu - Compact Electromechanical Impedance Analyzer for Structural Health Monitoring - Compact Electromechanical Impedance Analyzer for Structural Health MonitoringThu, 16 Aug 2012 13:42:32 GMTtechnology@sc.edu of novel method for preparation of PEM fuel cell electrodes, 16 Aug 2012 13:42:30 GMTtechnology@sc.edu - (Comprehensive Management System for Managing the National Geodeic Survey Control Stations) - (Comprehensive Management System for Managing the National Geodeic Survey Control Stations)Thu, 16 Aug 2012 13:42:29 GMTtechnology@sc.edu for Enhanced Hydrogen Adsorption/Desorption Kinetics in Complex Hydrides Reference #: 00395 The University of South Carolina is offering licensing opportunities for this technology. Invention Description: This technology is a new method for producing doped metal hydride compounds that has been shown to improve hydrogen storage characteristics. Advantages and Benefits: The method is an improvement from the traditional ball milling techniques and achieves enhanced distribution and uniformity of materials. As a result, the composition is a fused combination of dopants and metal hydrides. The fused compositions have excellent physical stability and desirable absorptio...Thu, 16 Aug 2012 13:42:28 GMTtechnology@sc.edu Hydrogen Storage Materials, 16 Aug 2012 13:42:27 GMTtechnology@sc.edu Method of Eliminating Forward Voltage Drift in SiC PiN and PN Diodes, 16 Aug 2012 13:42:26 GMTtechnology@sc.edu and Use of Novel Inhibitors and Inactivators of Protein Arginine Deiminases, 16 Aug 2012 13:42:25 GMTtechnology@sc.edu PRO) - Plant Viral Genes Capable of Boosting the Replication of a Broad Range of Other Viruses, 13 Aug 2012 14:07:34 GMTtechnology@sc.edu - HCP+) - A Method for High Level Expression of Gene Products in Plants, 13 Aug 2012 14:07:34 GMTtechnology@sc.edu Defect Delineation in SiC Wafers Using Optical Stress Technique, 13 Aug 2012 14:07:34 GMTtechnology@sc.edu of Functional Nanowires via Virus Assembly, 13 Aug 2012 14:07:33 GMTtechnology@sc.edu Myocardium, 13 Aug 2012 14:07:33 GMTtechnology@sc.edu Method for Decomposing Toxic Organic Pollutants, 13 Aug 2012 14:07:31 GMTtechnology@sc.edu structural health monitoring, diagnostics, and prognostics system utilizing smart active sensors with embedded intelligence and wireless installation, 13 Aug 2012 14:07:30 GMTtechnology@sc.edu Synthesis of (+)-Fusarochromanone, 13 Aug 2012 14:07:29 GMTtechnology@sc.edu Catalysts Supported on Modified Carbon Substrates for PEMFC Cathodes, 07 Aug 2012 13:16:27 GMTtechnology@sc.edu of Gene Expression Using Capillary Electrophoresis with Laser-induced Fluorescence (CE-LIF), 07 Aug 2012 13:16:26 GMTtechnology@sc.edu Carbon Catalysts for Oxygen Electroreduction in PEMFC Cathodes, 07 Aug 2012 13:16:26 GMTtechnology@sc.edu Silver Vanadium Oxide for High Performance Primary Lithium Batteries, 07 Aug 2012 13:06:42 GMTtechnology@sc.edu for Implementing MOC Classification via Streak Imaging of Particles Reference #: 00906 The University of South Carolina is offering licensing opportunities for this technology. Potential Applications: Characterization or classification of phytoplankton Advantages and Benefits: Novel method for the characterization of phytoplankton-the method is able to characterize MOEs and mimic linear discriminant analysis (LDA) results based on plankton spectroscopy Invention Description: Phytoplanktons are the autotrophic components of the plankton community. They represent the basic organic compounds of natural waters. Their diagnosis and characterization are impo...Mon, 16 Jul 2012 10:11:24 GMTtechnology@sc.edu, Non-Toxic Scrubber for Removing Carbon Dioxide from Atmospheric Air Reference #: 00712 The University of South Carolina is offering licensing opportunities for a high-efficiency and non-toxic CO2 scrubbing system configured to remove the variable CO2 in atmospheric air. Potential Applications: This technology can be used to improve efficiency and consistency of processes using CO2 scrubbing systems. Advantages and Benefits: Is highly efficient and non-toxic Provides for stringent control of pCO2 Removes the variable CO2 in atmospheric air Problem: Given the massive use of fossil fuels to provide energy for our world population, concerns about the ...Mon, 16 Jul 2012 10:11:24 GMTtechnology@sc.edu Manipulation of Gene Expression Via the Micro-RNA Pathway Reference #: 00346 The University of South Carolina is offering sub-licensing opportunities for a plant biotechnology for the regulation of gene expression by using miRNA pathways to silence deleterious or non-desired genes. Potential Applications This technology is useful in a variety of situations where it is desirable to control the expression of a specific gene in a plant. Advantages and Benefits: Can be used to increase the expression of beneficial or desired plant genes and decrease the expression of deleterious or undesired plant genes Provides an alternative to the use of RNA si...Tue, 10 Jul 2012 08:47:33 GMTtechnology@sc.edu of Osteoarthritis and Other Pathological Calcifications Reference #: 00698 Title: Prevention of Osteoarthritis and Other Pathological Calcifications The University of South Carolina is offering licensing opportunities for a technology that advances the study and treatment of osteoarthritis and other pathological calcifications. Potential Applications: In addition to the treatment of osteoarthritis, chondrocalcinosis, and atherosclerosis, this technology can have applications in the areas of oncology, inflammation and virology. Advantages and Benefits: Provides a fully functional model of the first steps in protein-membrane interaction Lowe...Mon, 09 Jul 2012 13:40:51 GMTtechnology@sc.edu Method to Increase and Control Carrier Lifetime in SiC Reference #: 00694 Invention Description: This invention is a method to use Silicon Carbide (SiC) epilayers for bipolar devices, which gives the user control of the carrier lifetime. Background: Until now, there has been no method for controlling or improving the carrier lifetime using the Chemical Vapor Deposition (CVD). Carrier lifetime is a key parameter of bipolar devices. A long life is useful for modulating the conductivity, while a shorter lifetime is better for switching devices with lower switching losses. Therefore, it is incredibly important to have a controlled process where ...Mon, 09 Jul 2012 13:40:51 GMTtechnology@sc.edu Gene Polymorphisms in Cancer Disease Diagnosis, Prevention and Treatment Reference #: 00687 The University of South Carolina is offering licensing opportunities for a direct nucleotide sequencing strategy that identifies polymorphisms of CD44, which may account for 80% of breast cancer cases. Potential Applications: This nucleotide sequencing strategy is used in the prevention, diagnosis, and treatment of breast cancer. Advantages and Benefits: Aids in the diagnosis of breast cancer at earlier stages leading to higher survivability Identifies CD44 polymorphism which may account for 80% of breast cancer cases Background: Currently, two breast cancer suscepti...Mon, 09 Jul 2012 13:40:50 GMTtechnology@sc.edu A Robust Paradigm for In Vitro Screening and Discovery of Drugs for the Prevention of Osteoarthritis and Pathological Biomineralization and Atherosclerosis, 09 Jul 2012 13:40:46 GMTtechnology@sc.edu of cryoablation using a thermally responsive nanocapsule for controlled drug delivery #: 00782Invention Description:This invention is a product and method to integrate cryoablation with controlled drug delivery using a thermally responsive nanocapsule to achieve complete cancer destruction in the iceball and simultaneously minimize the systemic drug cytotoxicity. Because of characteristics specific to the nanocapsule, a significant drug release into the cytosol of cancer cells can be achieved under cryoablation, which can significantly augment cryoinjury to ensure complete destruction of the whole frozen tumor.Potential Applications:Augmented cryoablation has the pote...Thu, 05 Jul 2012 12:52:42 GMTtechnology@sc.edu MOS-driver Compatible JFET Structure with Enhanced Gate Source Characteristics Reference #: 00780 Invention Description: This invention is a modified Junction Field Effect Transistor (JFET) gate structure that allows the gate to be driven by a conventional Metal Oxide Semiconductor Field Effect Transistor (MOSFET) gate driver. Prior-art JFETs have different gating requirements from MOSFETs because of the diode between gate and source. This invention reduces the amplitude of the gate current needed to control the device because in the present invention the gate current is a unipolar current (only one carrier type), rather than a bipolar current (both carrier types) as ...Thu, 05 Jul 2012 12:52:41 GMTtechnology@sc.edu and Controlled Release of Small Molecules for Intracellular Delivery using Thermally Responsive Nanocapsules, 05 Jul 2012 12:52:41 GMTtechnology@sc.edu Credentialing Using Veiled Certificates, 05 Jul 2012 12:52:41 GMTtechnology@sc.edu Inhibitors and Activity-based Probes for the Protein Arginine Methyltransferases Reference #: 00771 Invention Description: The present invention is a potent, irreversible inhibitor, targeting protein arginine methyltransferase 1. Inhibition studies have demonstrated that the inhibitor is a potent and selective inactivator of the enzyme. This inhibitor covalently modifies an active site residue on the enzyme. Potential Applications: This inhibitor could be a vital tool in the treatment of heart and vascular diseases. By regulating the levels of ADMA, NO synthesis can be increased, leading to improved vascular homeostasis. It is also believed that this inhibitor, or a ...Thu, 05 Jul 2012 12:52:40 GMTtechnology@sc.edu to Stand Transfer Data Collection #: 00770Background:Health care needs and costs are estimated to rise in parallel with the rapidly growing aging population. When an older adult becomes dependent or disabled, family and health care providers experience significant financial, personal, and emotional burdens. Using indicators to predict approaching disabilities in older adults will allow for intervention and prevention, thereby reducing the burdens and costs associated with adult dependency. For instance, the capacity to stand up from a chair is an indicator of physical motor capabilities for older adults.Invention Des...Thu, 05 Jul 2012 12:52:40 GMTtechnology@sc.edu Method to Synthesize Porous Hollow Metal Oxide using "Self-rising" Approach Reference #: 00768 Invention Description: This invention is a method for creating a hollow structure following a "self-rising" approach, which is virtually a modified evaporation-induced self-assembly method. Development/Demonstration / Validation: This method was applied to cobalt oxide showed high crystallization. SEM imaging indicated sphere formation with 5 µm layers composed of spheres with diameters of 1 µm. TEM analysis has shown porous hollow spheres with very thin shells, some with intact or broken sphere morphology. High magnitude TEM exhibited small particles around 10nm that ...Thu, 05 Jul 2012 12:52:40 GMTtechnology@sc.edu of Delta Opioid Receptor Expression for Pain Management Reference #: 00766 Invention Description: The invention involves the use of a human herpes simplex virus as a vector to decrease expression of Delta Opioid Receptors (DORs) in Dorsal Root Ganglia (DRG) neurons as a treatment for acute and chronic pain and to enhance opioid analgesia. Potential Applications: Decreasing expression of DORs should increase the endogenous pain-suppressing mechanism, leading to a reduction in pain. This approach will allow for direct reduction of pain as well as a reduction in the dose of opioid required to produce analgesia, thus limiting opioid-associated sid...Thu, 05 Jul 2012 12:52:39 GMTtechnology@sc.edu Energy Harvesting Systems and Methods #: 00758The University of South Carolina is offering licensing opportunities for this technology.Potential Applications:The invention is intended to provide energy harvesting for devices which cannot be connected to an energy source directly and for sensors in electric power systems.Advantages and Benefits:Traditional modes of energy supply, such as batteries, have not been able to sufficiently provide the continuous or intermittent power needed by wireless sensors and other miniature devices. The invention is intended to overcome the problems presented by current technology by meeti...Thu, 05 Jul 2012 12:52:38 GMTtechnology@sc.edu Bottle Apparatus for Improvement of Suckling, 05 Jul 2012 12:52:37 GMTtechnology@sc.edu Mapping Technique for Evaluation of Bioprosthetic Heart Valves, 05 Jul 2012 12:52:37 GMTtechnology@sc.edu Preferential Oxidizer of Carbon Monoxide in Fuel Cell Reformate Reference #: 00740 The University of South Carolina is offering licensing opportunities for this technology. Potential Applications: Removal of carbon monoxide from reformate hydrogen providing power to PEM fuel cells Advantages and Benefits: Minimal power consumption PEMFC performance retained because Pt anode unaffected by CO in reformate hydrogen Invention Description: Hydrogen (H2) fueled proton exchange membrane fuel cells (PEMFC) offer an efficient alternative electrical power source for portable appliances. As hydrogen storage is a challenge, recent advances in micro refo...Thu, 05 Jul 2012 12:52:37 GMTtechnology@sc.edu for Making Layered Mixed-Metal Phosphonates for High Dielectric Strength Polymer Nanocomposites, 05 Jul 2012 12:52:35 GMTtechnology@sc.edu for Near UV AIGaN/GaN UV LEDs #: 00731The University of South Carolina is offering licensing opportunities for this technology.Potential Applications:Luminescence, or the absorption of energy with subsequent emission of light in the visible part of the light spectrum, is the basis of a broad range of applications such as cathode ray tubes, projection televisions, fluorescent tubes and lighting and x-ray and ionizing radiation detectors for medical and technical applications. The new families of phosphors introduced by the present invention can be used to make white-light emitting devices by exposing an appropriat...Thu, 05 Jul 2012 12:52:35 GMTtechnology@sc.edu Health Monitoring Software and Hardware Reference #: 00730 Invention Description: The present invention is improved apparatus and methodologies for monitoring structural integrity. More specifically, the invention relates to apparatus and methodologies employing ultrasonic devices and associated analysis software to perform, investigations of a structure. Potential Applications: Structural health monitoring (SHM) is a method of determining the health of a structure from the readings of an array of permanently-attached sensors that are embedded into the structure and monitored over time. Advantages and Benefits: While various i...Thu, 05 Jul 2012 12:52:35 GMTtechnology@sc.edu Method for Tissue-Engineering Organ Building Blocks Reference #: 00727 Invention Description: Dr. Jay Potts of the USC School of Medicine has collaborated with Dr. Robert Gourdie from the Medical University of South Carolina to develop a new method for generating tissue-engineered rings (toroids) of aligned contractile cells in vitro. The method provides a novel approach to directing self-organized morphogenetic principles that are intrinsic to 3D networks of coupled cells. Background: Body organs display complex shapes, surfaces, and internal structures including blood vessels. Coupled to morphological complexity, the component tissues of...Thu, 05 Jul 2012 12:52:34 GMTtechnology@sc.edu Induced Activation of Fusarochromanone and its Derivatives for their Use in the Diagnosis and Treatment of Cancer Reference #: 00718 The University of South Carolina is offering licensing opportunities for an exciting advancement in cancer treatment. Fusarochromanone is a photodynamic therapy that targets cancer cells without destroying healthy cells. It is effective in low doses and has limited side effects. Potential Applications: Fusarochromanone can be used in the treatment of a variety of cancers. Advantages and Benefits: Kills targeted tumor cells without killing normal cells Can be administered locally and in low doses Limited side affects Background: Cancer is the leading cause of dea...Thu, 05 Jul 2012 12:52:34 GMTtechnology@sc.edu Alkalinity Measuring Apparatus Utilizing Reverse Gran Titration, 05 Jul 2012 12:52:34 GMTtechnology@sc.edu Passivation Induced Dispersion of Carbon Nanotubes and Graphene #: 00943The University of South Carolina is offering licensing opportunities for this technologyPotential Applications:Dispersion of carbon nanotubes (CNTs) into different media both in research and practiceAdvantages and Benefits:Very efficient in dispersing MWCNTs Excellent dispersion of MWCNTs can be achieved with only 2h ultra-sonication after HP, which is much shorter than the conventional ultrasonic method that requires 10hr This method offers opportunities for dispersing a series of materials which tend to bundle together due to dangling bond, such as Graphene Unlike other sur...Thu, 05 Jul 2012 09:58:43 GMTtechnology@sc.edu Spectroscopy Using a Spatial Heterodyne Spectrometer Reference #: 00935 The University of South Carolina is offering licensing opportunities for this technology Potential Applications: Ideal for deep-UV laser excitation Pure rotational or ro-vibrational Raman measurements Planetary lander/rover measurements where the wide area collection capability of the instrument allows large areas of the surface to be measured quickly with no loss of spectral resolution Advantages and Benefits: The SHS Raman spectrometer has many unique advantages over all previously reported Raman spectrometers. Typical examples include: [A] Advantages over...Thu, 05 Jul 2012 09:58:43 GMTtechnology@sc.edu of Making Redox Materials for Solid Oxide Redox Flow Battery, 05 Jul 2012 09:58:42 GMTtechnology@sc.edu Method for Reduction and/or Elimination of Basal Plane Dislocations Close to Epilayer/Substrate Interface in Growth of SiC Epitaxial Films Reference #: 00932 The University of South Carolina is offering licensing opportunities for an optimized process for the pre-treatment of the SiC substrate to reduce or eliminate basal plane dislocation and in-grown stacking faults in SiC epitaxial films for the fabrication of state of the art electronics and optical devices. This process offers significant advantages over current techniques because it preserves high BPD conversion rate and is simple (three-minute treatment), non-destructive, and highly efficient process. Advantages and Benefits: Simple, non-destructive, fast, and highly e...Thu, 05 Jul 2012 09:58:42 GMTtechnology@sc.edu and compact hardware for logging power consumption of portable equipment Reference #: 00927 The University of South Carolina is offering licensing opportunities for this technology. Potential Applications: Power logger for synchronous monitoring and logging of power consumption in portable electronic equipment Specifically designed to be compatible with military radios such as PRC-152, PRC-153, PRC-117 and a whole range of other equipment Advantages and Benefits: A wide range of advantages including low power consumption, long duration data logging (up to 100 hrs.), high accuracy real-time clock, and unique device identification number Invention Descr...Thu, 05 Jul 2012 09:58:42 GMTtechnology@sc.edu Sulfur-Tolerant Anode Material for Direct Hydrocarbon Solid Oxide Fuel Cells Reference #: 00920 The University of South Carolina is offering licensing opportunities for this technology Potential Applications: The novel material acts as a promising anode material for high performance SOFCs with high tolerance towards carbon deposition and sulphur poisoning to efficiently convert practical fuels into electricity. Advantages and Benefits: The novel material acts as a SOFC anode material that has high electrode performance. It can simultaneously display both good sulfur tolerance and catalytic activity for hydrogen and hydrocarbon oxidation. Invention Descrip...Thu, 05 Jul 2012 09:58:41 GMTtechnology@sc.edu with Multiple Attached Polymer Assemblies and Use Thereof in Polymer Composites #: 00918The University of South Carolina is offering licensing opportunities for improved methods for synthesizing nanoparticles with multiple polymer assemblies attached.Potential Applications: This technology can be used in composites with improved mechanical properties or optically clear composites. It may also be used in biological and antibacterial applications.Advantages and Benefits:Improves the dispersion of nanoparticles in an organic polymer matrix Allows synthesis of nanoparticles with multiple polymer assemblies attached Nanoparticles with multiple polymer assemblies atta...Thu, 05 Jul 2012 09:58:41 GMTtechnology@sc.edu Analysis of MOC streak-camera images Reference #: 00907 The University of South Carolina is offering licensing opportunities for this technology Potential Applications: 1. Interpretation of results of Phytoplankton characterization procedure 2. Underwater monitoring and tagging of phytoplankton Advantages and Benefits: Ability to not only monitor but also discriminate between different phytoplankton taxa or discern cell size Ability to automatically detect and analyze the "barcode-like" patterns as well as sizes/shapes of the plankton streaks and assign a class to the plankton where possible Invention Description: ...Thu, 05 Jul 2012 09:58:40 GMTtechnology@sc.edu Oxide Redox Flow Battery #: 00898The University of South Carolina is offering licensing opportunities for this technology.Potential Applications:Has application in the large-scale stationary electricity storage for power generation industry.Advantages and Benefits:Maintains high efficiency levels that designated it as an energy-efficient electricity storage It utilizes a Me/MeOx redox couple to store H2 produced by an SOEC on-cell during the charging cycle. This capability is clearly advantageous over combined SOFC-SOEC storage device where the H2 produced by SOEC must be either instantaneously consumed by S...Thu, 05 Jul 2012 09:58:39 GMTtechnology@sc.edu Mixed Proton and Carbonate Ion Conductor #: 00897The University of South Carolina is offering licensing opportunities for this technology.Invention Description:Yttrium-doped barium zirconate (BZY) is now considered as an alternative to the oxygen-ion conductor electrolytes conventionally used in IT-SOFCs due to its higher bulk proton conductivity at low temperatures.BZY has not been fully exploited until now despite its excellent chemical stability because, when prepared as a ceramic polycrystalline material, it suffers from difficult sintering and proton conductivity is decreased by grain boundaries, which have a blocking ...Thu, 05 Jul 2012 09:58:39 GMTtechnology@sc.edu Cationic Compounds and Polymers and their Methods of Preparation, 05 Jul 2012 09:58:37 GMTtechnology@sc.edu Double Precision Floating Streaming Accumulator Architecture #: 00890The University of South Carolina is offering licensing opportunities for a double precision floating point stream accumulator.Invention Description:This invention is a SpMV architecture based on a novel streaming reduction circuit and a specialized cache optimized for CSR data. This architecture is implemented on the Convey HC-1, a self-contained heterogeneous system containing a Xeon-based host and an FPGA-based co-processor board with four user programmable Virtex5-LX330 FPGAs. A CSR sparse matrix-vector multiplier was configured and its implementation was analyzed on the C...Thu, 05 Jul 2012 09:58:37 GMTtechnology@sc.edu Hazard Assessment Tool (IHAT) Reference #: 00889 The University of South Carolina is offering licensing opportunities for this technology Potential Applications: Rather than bogging users down in the process of spatial data collection, analysis, and mapping activities, the IHAT will ultimately enable planners and analysts to spend more time creating effective planning and mitigation strategies and programs based on sound scientific (geospatial) analysis. Advantages and Benefits: Data and outputs are not only easily ingested into federally-mandated hazard mitigation plans, but the data also enables users to easily c...Thu, 05 Jul 2012 09:58:37 GMTtechnology@sc.edu Peptide Derived from Human Apolipoprotein E Inhibits Hepatitis C Virus Entry Reference #: 00885 The University of South Carolina is offering licensing opportunities for this novel method of blocking and/or treating Hepatitis C Virus. Invention Description: This invention is a human apolipoprotein E (apoE) peptide, designated hEP. hEP blocks Hepatitis C Virus (HCV) entry into hepatocytes. This peptide specifically blocks HCV entry at the attachment step and is effective at sub-micromolar concentrations. Analyses of hEP mapped its anti-HCV activity to a 33 amino acid-long region that harbors the receptor binding domain of human apoE. These results highlight the pot...Thu, 05 Jul 2012 09:58:37 GMTtechnology@sc.edu a Member of a New Scintillator Materials Family (MO4)FAnBm with M=B, Al, Si, P, S, Cr, V, Nb, Ta, Zr, H, 05 Jul 2012 09:58:36 GMTtechnology@sc.edu Zn2SnO4/MnO2 Core/Shell Nanocable-Carbon Microfiber Hybrid Composites for Energy Systems #: 00882The University of South Carolina is offering licensing opportunities for this the use of MnO2 in creating sustainable and renewable power sources.Potential Applications:Dr. Li’s research suggests that a MnO2/ZTO/CMF composite with hierarchical architecture is very promising for next generation, high-performance, flexible super-capacitors.Advantages and Benefits:• Low cost of MnO2• Environmental friendliness of MnO2• Natural abundance of MnO2Invention Description:To meet the urgent need for sustainable and renewable power sources in the modern electronic industry, many efforts...Thu, 05 Jul 2012 09:58:36 GMTtechnology@sc.edu Competitive PLK 1 Polo-dox Domain Inhibitors as Anti-tumor Therapeutics #: 00881 The University of South Carolina is offering licensing opportunities for a PLK1 polo-box domain inhibitor that makes cancer treatment more effective by targeting cancer cells for destruction while alleviating the harmful therapeutic toxicity that occurs from the use of existing remedies.Potential Applications:This therapy opens new therapeutics for cancer treatment without the traditional effects of toxicity to healthy cells.Advantages and Benefits:Is non-ATP competitive Selectively targets the polo-box domain of PLK1 Is not toxic to normal cells Background:Cancer is the lea...Thu, 05 Jul 2012 09:58:36 GMTtechnology@sc.edu of the Remaining Life of a Structural System Based on Acoustic Emission Signals, 05 Jul 2012 09:58:36 GMTtechnology@sc.edu of Treating a Water Sample or a Substrate to Remove Organic Compounds Reference #: 00875 Keywords: Advanced oxidation processes (AOPs), hydroxyl radical, treatment/remediation, sustainable oxidation Invention Description: The subject invention is a system of equations (a model) that can be used to develop sustained free radical oxidation processes using low energy, environmentally sustainable feedstocks such as Fe salts, atmospheric oxygen, and naturally occurring organic molecules. Background: The oxidation of aqueous Fe(II) by atmospheric dioxygen is associated with the production of several reactive oxygen species (ROS). These include hydrogen peroxide...Thu, 05 Jul 2012 09:58:35 GMTtechnology@sc.edu Modified Ceramic Anodes for Direct-Methane Solid Oxide Fuel Cells, 05 Jul 2012 09:58:35 GMTtechnology@sc.edu and Sensor for the Detection of Active Carbon Filters Degradation with EMIS-ECIS PWAS #: 00872Background:Combined use of electromechanical impedance spectroscopy (EMIS) and electrochemical impedance spectroscopy (ECIS) with piezoelectric wafer active sensors (PWAS) for degradation detection in active carbon filters offers a revolutionary new approach to detect electrical and mechanical changes in active carbon filters. PWAS are the enabling technology for active structural health monitoring (SHM) systems. The motivation for this development is to give a non-intrusive in-situ evaluation method to improve the safety of active carbon filter systems. Invention Description...Thu, 05 Jul 2012 09:58:34 GMTtechnology@sc.edu of Cobaltocenium-containing Vinyl Monomers and Their Polymers, 05 Jul 2012 09:58:34 GMTtechnology@sc.edu (trademark) is an algorithm for measure the social vulnerability of places and the people who live there to hazards and extreme events, 05 Jul 2012 09:58:33 GMTtechnology@sc.edu Carbonate-ion and Oxide-ion conducting membranes and reactors for H2 production with zero CO2 emission Reference #: 00856 Invention Description: Steam reforming of methane is the most common hydrogen production method in commercial use today. However, one of the major byproducts of the steam reforming process is CO2, a significant contributor to global warming and climate change. Capturing CO2 has therefore become a paramount task for the hydrogen producing industries. This technology involves a novel process that produces pure hydrogen without emissions of CO2. The overall system description and necessary modifications/variations would require limited technological sophistication. The f...Thu, 05 Jul 2012 09:58:32 GMTtechnology@sc.edu Energy Harvesting for Non-Intrusive Monitoring of Power Systems, 05 Jul 2012 09:58:32 GMTtechnology@sc.edu screen that determines tumors with fumarate hydratase mutations Reference #: 00849 Invention Description: Dr. John Baynes and Dr. Norma Frizzel, along with researchers from Oxford University, have developed a novel rapid diagnostic immunohistochemical screen to identify tumors that have mutations in the fumarate hydratase gene. The screen can detect genetic mutations in less than three hours and allows for retrospective screening of archival paraffin embedded tumor samples. Potential Applications: This invention provides diagnostic screening to identify tumors with specific genetic mutations. It may also be possible to use the screen to identify prec...Thu, 05 Jul 2012 09:58:31 GMTtechnology@sc.edu Protein Arginine Deiminase (PAD) Activity in Human Tissues and SERA #: 00844BackgroundThe abundance of citrullinated proteins in human tissue has become a hallmark of many diseases, including cancer, rheumatoid arthritis, colitis, and multiple sclerosis. Proteins are citrullinated by a class of enzymes termed Protein Arginine Deiminases (PADs), which convert peptidyl-arginine to peptidyl-citrulline through an enzymatic reaction called deimination. Developing PAD inhibitors has become a focus of much research due to the apparent roles of PADs in the aforementioned diseases. Invention Description:Dr. Paul Thompson and his research team have developed a...Thu, 05 Jul 2012 09:58:31 GMTtechnology@sc.edu White-Light Phosphors #: 00838The University of South Carolina is offering licensing opportunities for this technologyPotential Applications:Frequency up-conversion luminescence has great potential applications in diode-pumped all-solid-state visible lasers, highly efficient next-generation lighting, near-IR photon detectors, high power fiber up-conversion lasers, nm-sized biological labels and new emissive displays. Up-to-date rare earths have mainly been doped into oxyfluoride glasses since oxyfluorides combine the favorable low phonon energy and high up-conversion efficiencies with the high mechanical ...Thu, 05 Jul 2012 09:58:29 GMTtechnology@sc.edu of RNF138 Interaction with RAD51D and Basis for Discovery of RNF138 E3 Ligase Inhibitors Reference #: 00837 Invention Description: Deficiencies in DNA damage response and repair pathways that manage DNA double-strand breaks (DSBs) are associated with cancer susceptibility. RAD51D, a member of the RAD51 protein family, is required for homology-directed repair of both DNA DSBs and interstrand crosslinks. The protein also maintains chromosome and telomere integrity. RAD51D participates in the "BRCA2 complex" and interacts directly with RAD51C and XRCC2. Invention Description: Dr. Douglas Pittman has identified RNF138, a mediator of homology-directed DNA DSB repair that functions ...Thu, 05 Jul 2012 09:58:29 GMTtechnology@sc.edu Nano-Electric Field Implanted Generator for Modulating Wound Healing Response, 05 Jul 2012 09:58:29 GMTtechnology@sc.edu Power Transfer to Embedded Sensors #: 00835The University of South Carolina is offering licensing opportunities for this technologyPotential Applications:Wireless embedded sensors for infrastructure monitoring in bridges, buildings, pipelines, power lines, and dams Hazardous waste processing and removal facilities Nuclear waste monitoring Biomedical applications Advantages and Benefits:Futuristic low-cost solutions that can be embedded within a RFID infrastructure (when the structure itself is built) Dual-function humidity sensor antenna that can be easily integrated within existing or future wireless transceiver modu...Thu, 05 Jul 2012 09:58:28 GMTtechnology@sc.edu that would collapse into non-convex structures Reference #: 00832 Invention Description: Dr. Arash Kheradvar has developed a type of stent that can be collapsed into a non-convex structure. This is accomplished by transforming the primary convex cross section of an expanded stent into a non-convex cross section when collapsed, thus reducing the overall profile size of a collapsed stent through minimizing the intra-stent space. A convex cross section is a polygonal shape with the interior as a convex set. A polygon that is not convex is called concave or reentrant. A concave polygon will always have an interior angle that measures greate...Thu, 05 Jul 2012 09:58:28 GMTtechnology@sc.edu Analysis of the CDK4/cyclin D1 Substrate Recognition Site and Basis for p27 and Inhibitor Binding Reference #: 00829 Invention Description: An alternative strategy for inhibition of the cyclin dependent kinases in anti-tumor drug discovery is afforded through the substrate recruitment site on the cyclin positive regulatory subunit. This approach offers the potential for generating cell cycle-specific CDK inhibitors and to reduce the inhibition of transcription mediated through CDK7 and 9, commonly observed with ATP competitive compounds. While highly potent peptide and small molecule inhibitors of CDK2/cyclin A, E substrate recruitment have been reported, little information has been gen...Thu, 05 Jul 2012 09:58:27 GMTtechnology@sc.edu Hydrogen Permeation in Nanocrystalline Proton Conducting Ceramics of the Form SrCeO3 Reference #: 00828 The University of South Carolina is offering licensing opportunities for this technology Potential Applications: Implementing this technology to create dense, nanocrystalline ceramics or thin films on porous supported substrates would result in enhanced hydrogen permeation membranes. Advantages and Benefits: Because electron conductivity has been demonstrated to be the limiting factor for hydrogen permeation, any increase in this value results in enhanced permeation: In oxide structures exposed to a reducing hydrogen atmosphere, oxygen is removed from the SrCeO3 lat...Thu, 05 Jul 2012 09:58:27 GMTtechnology@sc.edu Heat Capacity Changes Due to Surface Inconsistencies using High Absorbance Spectral Regions in the mid-IR, 05 Jul 2012 09:58:27 GMTtechnology@sc.edu Surface Stains Using High Absorbance Spectral Regions in the mid-IR, 05 Jul 2012 09:58:26 GMTtechnology@sc.edu Software Tool for Computing the Net Present value of Carbon Credits for Tidal and Constructed Wetlands, 05 Jul 2012 09:58:26 GMTtechnology@sc.edu Mixed Ionic and Electronic Conductor Based on Sr2Fe2-xMoxO6 Double Perovskite, 05 Jul 2012 09:58:26 GMTtechnology@sc.edu Novel Method to Fabricate High Performance Tubular Solid Oxide Fuel Cells #: 00819Invention Description:This invention is a proprietary process to produce tubular solid oxide fuel cells (SOFCs). SOFCs have long been considered promising candidates for the next generation energy conversion devices, due to their high electrical conversion efficiencies, environmental benignity, and fuel flexibility. The tubular SOFCs produced with the subject process realize that promise. They can be operated in reversible (both fuel cell and electrolysis) mode with high cell performance and excellent durability. As such, they offer an economically viable alternative for larg...Thu, 05 Jul 2012 09:58:25 GMTtechnology@sc.edu Biometrics, 05 Jul 2012 09:58:25 GMTtechnology@sc.edu Mixed Carbonate Ions and Electrons Conducting Membranes and Reactors for CO2 Separation and Capture Reference #: 00815 Background: The technical approach to reduce CO2 emissions is simply to avoid the emissions to the atmosphere by capturing and storing it at either the pre-combustion or post-combustion stage. At either stage, CO2 has to be separated from either a reducing fuel stream (pre-combustion) or an oxidizing flue gas stream (post-combustion) into a highly concentrated form, from which CO2 can then be further compressed into a liquid form and stored via geologic sequestration. The technologies available for CO2 separation include mechanical scrubbing and poly-amine solvent-based p...Thu, 05 Jul 2012 09:58:25 GMTtechnology@sc.edu Imaging in the Thermal Infrared for Chemical Contrast Enhancement Reference #: 00811 Invention Description: This technique relies on a thermal imaging system adapted with a modulated light source. Chemical contrast in the image is enhanced by using AC responses as well as lock-in amplifier techniques to acquire both reflection and emission data about the sample. Potential Applications: One skilled in the art will recognize that this technique can be used for, but is not limited to, the imaging of blood or proteins. Data would suggest this technique could be used to identify any substance that has a unique spectral profile. Advantages and Benefits: Dat...Thu, 05 Jul 2012 09:58:24 GMTtechnology@sc.edu and Applications of Well-Defined Polymers Derived From Rosin #: 00810Invention Description:The present invention provides an entirely new approach for developing well-defined polymers for the use of rosin in applications ranging from thermoplastic resins to polymer composites. More particularly, methods are provided for preparing well-defined polymers comprising rosin wherein: (i) block copolymers, random copolymers, graft copolymers, star copolymer, or organic/inorganic hybrids contain at least one polymerized monomer derived from rosin; and (ii) rosin-containing block copolymers, random copolymers, graft copolymers, star copolymer or organic...Thu, 05 Jul 2012 09:58:24 GMTtechnology@sc.edu Electrode Design for Low Temperature Direct-Hydrocarbon Solid Oxide Fuel Cells #: 00808The University of South Carolina is offering licensing opportunities for a Novel Electrode Design for Low Temperature Direct-Hydrocarbon Solid Oxide Fuel CellsInvention Description:Among the perovskite-type cathode materials for SOFCs, cobaltite has the highest surface oxygen exchange coefficient, oxide ion conductivity as well as electronic conductivity at reduced operating temperatures. These are the factors favorable for oxygen reduction reaction for a high performance cathode material. In order to overcome the barriers of thermal expansion mismatch as well as chemical int...Thu, 05 Jul 2012 09:58:23 GMTtechnology@sc.edu Nanowire Based Multifunctional Sensors Reference #: 00802 Invention Description: This technology is an indium-nitrogen (InN) nanowire (NW) based multifunctional V-shaped nanocantilever (VNC) sensor for detection of analyte molecules in ambient conditions and investigation of electrical signal propagation in neurons. The special shape and geometry of the nanowires, which can be achieved inexpensively through barrier patterning, allows not only their use as cantilevers, but also transduces their deflection from change in resistance between the two arms. A VNC can both dramatically improve detection sensitivity and provide a ready ...Thu, 05 Jul 2012 09:58:23 GMTtechnology@sc.edu High Throughput Assay For Discovering New Inhibitors of the GIRK1/4 Channel Reference #: 00792 Invention Description: Discovery of new drugs that act on the cardiac IK,Ach has been hampered by the absence of a cell-based high throughput screening system that utilizes IK,Ach. The present invention provides a high throughput methodology for discovering new drugs that bind to and inhibit IK,Ach. In this invention, cells expressing IK,Ach are plated in 96-well culture dishes and treated with potential drugs that inhibit IK,Ach. The activity of IK,Ach is then measured in the presence of muscarinic agent carbachol using a fluorescent imaging plate reader (FLIPR). Potent...Thu, 05 Jul 2012 09:58:21 GMTtechnology@sc.edu of Direct Growth Inhibition of Various Types of Cancer Cells by Fusarochromanone Reference #: 00337 The University of South Carolina is offering sub-licensing opportunities for a compound that shows promise for the treatment of cancer, arthritis, and other angiogenic diseases. The compound strongly inhibits tumor growth and is also effective in inhibiting angiogenesis. This unique combination of anticancer activity and anti-angiogenic activity makes this compound attractive for clinical development. Potential Applications: This invention offers promise for the treatment of cancer and angiogenic diseases, including arthritis. Advantages and Benefits: Particularly attrac...Thu, 05 Jul 2012 09:58:19 GMTtechnology@sc.edu Single-Pot Method for the Synthesis of Mono-Disperse Core-Shell Nanoparticles, 27 Jun 2012 13:05:37 GMTtechnology@sc.edu (~100 µm ) microcapsules for cell micro encapsulation Reference #: 00892 Background Alginate is one of the most widely used biomaterials for cell microencapsulation due to its natural origin and excellent biocompatibility. Alginate microcapsules can be coated with a polycation layer to increase stability and allow for further control of membrane permeability of the microcapsules. Poly-L-lysine (PLL) is the most studied and utilized polycation to produce alginate-PLL-alginate (APA) microcapsules. However, PLL induces cytokine production in monocytes and can cause cellular necrosis. Chitosan has attracted much attention as a replacement for PLL. ...Wed, 27 Jun 2012 13:05:35 GMTtechnology@sc.edu Arginine Deiminase Inhibitors as a Novel Therapeutic Strategy for Rheumatoid Arthritis, Cancer and Other Human Diseases, 27 Jun 2012 13:05:33 GMTtechnology@sc.edu PCR loading platform Reference #: 00675 The University of South Carolina is offering licensing opportunities for a platform that allows researchers to consistently and accurately reproduce small amounts of reaction mixes for real-time PCR. Potential Applications: This platform is used in real-time polymerase chain reaction experimentation. Advantages and Benefits: Shows the investigator exactly which wells have been loaded and which are to be loaded next No external light is applied, unlike previous devices which interfered with the florescent chemistries used in the PCR Extremely user-friendly and cost...Wed, 27 Jun 2012 13:05:30 GMTtechnology@sc.edu